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You ensure 90% or more of your creatures would not meet the conditions of the wipe, and you have an incredible answer to lots of creatures your opponents post up on the battlefield

List synced from Scryfall (is:gamechanger) impact from Playgroup tracked games.

That definitely has some synergies worth considering

Being only three mana means you can often play it on turn two and follow it up with big creatures that will draw you cards every turn from there on out

Hedron Detonator Hedron Detonators mostly used as a redundant copy of Reckless Fireweaver or Ingenious Artillerist, though worse than those cards since it only hits one opponent at a time

The +1/+1 counters/Food tokens are artifacts, so anything that counts artifacts will count them